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Physiology Research Groups

The Physiology Department has two main research focus areas: 1) Mechanisms of Systemic Diseases, Molecular Metabolism and Physiology and 2) Cancer Molecular Biology/Physiology.   Within these areas are research sub-groups focused on specific disease processes and physiologic concepts.

Mechanisms of Systemic Diseases, Molecular Metabolism and Physiology


Molecular Metabolism and Disease
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Focus: Understanding mechanisms accounting for disease development, progression and complications (retinopathy, osteoporosis, bone marrow pathology, artherosclerosis and neuroendocrine changes). Diabetes and Inflammatory bowel disease are focus areas. Faculty: Busik, Mohr, McCabe, Parameswaran

Diabetes and Obesity

Focus: Identifying how diet (high fat), diabetes, leptin, and inflammation impacts organ function directly and systemically. Faculty: Busik, Haslam, Mohr, Olson, McCabe, Parameswaran

Neurobiology/Physiology

Focus: Neural regulation of organ system function, including metabolism, intestinal motility, cardiovascular system, spinal cord regeneration, glaucoma, and Parkinson’s disease. Faculty: Wang, Weber, Kreulen, Schneider, Gallo, Cibelli

Cardiopulmonary Disease

Focus: Mechanisms of lung injury, cardiovascular disease and blood flow and potential treatment options. Faculty: Uhal, Robinson, Parameswaran, Meyer, Kreulen, Wiseman

Gastrointestinal Disease

Focus: Gastrointestinal function and disease, including inflammatory bowel disease, diabetes, cancer, cystic fibrosis, and bile atresia.  Faculty: Schneider, Parameswaran, Olson, Luckie, Li, McCabe, Xiao.

Musculoskeletal Disease

Focus: Mechanisms of muscle and bone adaptation to disease and aging. Faculty: Wiseman, Meyer, McCabe

Cancer Molecular Biology/Physiology Research


Breast Cancer and the Environment (click)

Focus: Understanding environmental and dietary factors that affect hormonal activity (estrogen and/or progesterone) and the development and progression of breast cancer. Faculty: Haslam, Yang

Breast Cancer Signaling Networks

Focus: Identifying the signaling pathways that lead to the development and progression of breast cancer. Faculty: Haslam, Gallo, Andrechek, Xiao, Yang

Lung Cancer

Focus: Mechanisms promoting lung cancer development and progression. Faculty: Yang

Liver Cancer

Focus: Mechanisms promoting liver cancer.  Faculty: Xiao


Common themes among the Physiology Research Groups include: Inflammation; Cell Signaling; Cell Growth, Differentiation and Death; Neuroendocrine Regulatory Pathways, and Metabolism.