Directory > Faculty
Keith J. Lookingland, Ph.D.
 |
Adjunct
Associate Professor of Physiology
Associate Professor of Pharmacology and Toxicology
Ph.D., University
of Maryland
|
Development of Neuroprotective Pharmacological Agents and Strategies
for the Treatment of Dopamine Neurodegenerative Disorders including
Parkinson's Disease and Restless Legs Syndrome
PUBLICATIONS:
Drolet, R.E., B. Behrouz,
K.J. Lookingland and J.L. Goudreau, 2004. Mice lacking á-synuclein
have an attenuated loss of striatal dopamine following prolonged
chronic MPTP administration. Neurotoxicology 25(5): 761-769.
Lookingland, K.J. and K.E. Moore, 2005. Functional neuroanatomy
of hypothalamic dopaminergic neuroendocrine systems. In "Handbook
of Chemical Neuroanatomy," Vol. 20, Chapter 8: 433-521.
Ni, W., C.S. Wilhelm, M. Bader, D.L. Murphy, K.J. Lookingland
and S.W. Watts, 2005. (+)-Norfenfluramine-induced arterial contraction
is not dependent on endogenous 5-HT or 5-HTT. J. Pharmacol. Exp.
Ther. 314(3): 953-960.
McCall, R.B., K.J. Lookingland, P.J. Bedard and R.M. Huff, 2005.
Sumanirole, a highly dopamine D2-selective receptor agonist: In
vitro and in vivo pharmacologic characterization and efficacy
in animal models of Parkinson´s disease. J. Pharmacol. Exp. Ther.
314(3): 1248-1256.
Drolet, R.E., B. Behrouz, K.J. Lookingland and J.L. Goudreau,
2006. Substrate-mediated enhancement of phosphorylated tyrosine
hydroxyase in nigrostriatal dopamine neurons: Evidence for a role
of á-synuclein. J. Neurochem. 96: 950-959.
Ni, W., K.J. Lookingland and S.W. Watts, 2006. Arterial 5-HT
transporter function is impaired in DOCA and LNNA but not spontaneously
hypertensive rats. Hypertension 48: 134-140.
Behrouz, B., R.E. Drolet, Z.A. Sayed, K.J. Lookingland, J.L.
Goudreau, 2007, Unique responses to mitchondrial complex I inhibition
in tuberoinfundibular dopamine neurons may impart resistance to
toxic insult. Neuroscience 147: 592-598.
OTHER PUBLICATIONS:
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