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Gerard Gebber, Ph.D.

Professor, Joint with Department of Pharmacology and Toxicology

One of the least understood aspects of autonomic neurobiology concerns the central mechanisms responsible for the control of sympathetic nerve discharges.  There is considerable data supporting the view that disturbances in control of autonomic nerve activity can contribute to the development or maintenance of hypertension, cardiac dysrhythmias, and other cardiovascular diseases.  Recent work demonstrates that different rhythms are evident in sympathetic nerve activity depending upon the experimental conditions.  The major objectives of the research in our laboratories are 1) to determine which regions of the brain contain the neurons responsible for the different rhythms in sympathetic activity, 2) to identify the interconnections of single neurons with activity correlated to sympathetic nerve activity, 3) to determine what role the different rhythms play in regulating vasomotor tone and in mediating complex and highly differentiated cardiovascular response patterns as occur during defense, exercise, and sleep.

Publications
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