Directory > Faculty
Kathleen A. Gallo, Ph.D.
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Professor, College of
Human Medicine, Joint with Department of Biochemistry
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Area
of Research Interest [PDF]
We recently identified a novel, intracellular
human protein serine/threonine kinase SPRK that upon overexpression
transforms cells and renders them competent to form tumors in
nude mice. We are studying the role of SPRK and of other novel
protein kinases in mammalian signal transduction and cancer.
PUBLICATIONS:
Gallo, K.A., M.R. Mark, Z. Wang, D.T. Scadden, Q. Gu and P.J.
Godowski. Identification and characterization of SPRK, a novel SH3 domain-containing
proline-rich kinase with serine/threonine kinase activity. J. Biol. Chem. 269:15092-15100,
1994.
Gaudino, G., A. Follenzi, L. Naldini, C. Collesi, M. Santoro,
K.A. Gallo, P.J.
Godowski and P.M. Comoglio. Ron is a heterodimeric tyrosine kinase receptor activated by
the HGR-homolog MSP. EMBO J. 13:3524-3532, 1994.
Other Publications
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