Kathleen A. Gallo, Ph.D.
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Professor, College of Human Medicine, Joint with Department of Biochemistry |
Area of Research Interest [PDF]
We recently identified a novel, intracellular human protein serine/threonine kinase SPRK that upon overexpression transforms cells and renders them competent to form tumors in nude mice. We are studying the role of SPRK and of other novel protein kinases in mammalian signal transduction and cancer.
PUBLICATIONS:
Gallo, K.A., M.R. Mark, Z. Wang, D.T. Scadden, Q. Gu and P.J. Godowski. Identification and characterization of SPRK, a novel SH3 domain-containing proline-rich kinase with serine/threonine kinase activity. J. Biol. Chem. 269:15092-15100, 1994.
Gaudino, G., A. Follenzi, L. Naldini, C. Collesi, M. Santoro, K.A. Gallo, P.J. Godowski and P.M. Comoglio. Ron is a heterodimeric tyrosine kinase receptor activated by the HGR-homolog MSP. EMBO J. 13:3524-3532, 1994.
Other Publications
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