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Angelica Leitmannova Liu, DrSc., Ph.D.

Visiting (Research) Professor
Overseas Coordinator, Center of Interface Sciences (CIS)
Professor of Biophysics at the Slovak Technical University in Bratislava, Slovak Republic
Professor of Biophysics at the Masaryk University in Brno, Czech Republic

Areas of Research Interest

Research objectives as well as the pedagogic work in the course PSL 420 are intended for advanced students and new researchers interested in membrane biophysics. The focus is on biophysical aspects of biological membranes. The area of membrane biophysics is perused from the origin of the lipid bilayer concept to membrane transport, electrochemistry, physiology, bioenergetics, and to membrane photobiology. Emphasis in the research is placed on theoretical and experimental model systems, as related to the structure and function of biomembranes.

The connecting thread among these topics is the experimental bilayer lipid membranes (planar BLMs, supported BLMs, and spherical liposomes). The basic principles of thermodynamics, kinetics, the Nernst-Planck equation, colloid and surface chemistry are applied to the above-listed topics of membrane biophysics. Some potential practical applications of self assembled lipid bilayers as biosensors are an essential part of the research work, of publications and of the PSL 420 course for advanced undergraduate and also for graduate students.

This is because of the fact that recent advances in microelectronics coupled with membrane research of the past decades have come of age and are poised for biotechnological exploitation. Many exciting new discoveries are happening in the interdisciplinary sciences. Membrane biophysics, membrane physiology and biosensors development are only few disciplines in this exciting area of the fast development and of the potential for the future.
Also, another important project is the international collaboration with Slovak Republic and Czech Republic in developing a Center of Interface Sciences (CIS) at the Department of Microelectronics, Faculty of Electrical Engineering and Information Technology of the Slovak Technical University in Bratislava during 1990s. This work was supported over 6 years by US AID grant in the middle of 1990s and continues until present in a number of joint publications, many international conferences' contributions, exchange of scientific expertise and common lectures in the interdisciplinary field between molecular biology and microelectronics.

Dr. A. Leitmannova Liu is author of 3 major book publications in biophysics, the first one with the Editorial office Alfa in the former Czechoslovakia in 1993 and 2 Elsevier book publications together with late Prof. Dr. H. Ti Tien in January 2000 and in February 2003. The URL of the latest book publication (February 2003) is:
http://www.elsevier.com/inca/publications/store/6/7/2/6/8/6/index.htt
For more details, visit the following URL:
http://www.msu.edu/user/ottova/planar_lipid_bilayers.html

She is also the editor of a book series with Elsevier, Amsterdam under the title: “Advances on Planar Lipid Bilayers and Liposomes”. Since the year 2005 already 5 volumes with a broad international participation were published under this title and much more are in the process of final preparation. The relevant URLs of this book series are:
http://www.elsevier.com/wps/find/bookdescription.cws_home/710269/description#description
http://www.elsevier.com/wps/find/bookseriesdescription.cws_home/BS_0336/description



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